Open Access News

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Sunday, January 01, 2006

Profile of JASPAR

D. Vlieghe and six co-authors, A new generation of JASPAR, the open-access repository for transcription factor binding site profiles, Nucleic Acids Research, January 1, 2006.
Abstract: JASPAR is the most complete open-access collection of transcription factor binding site (TFBS) matrices. In this new release, JASPAR grows into a meta-database of collections of TFBS models derived by diverse approaches. We present JASPAR CORE-an expanded version of the original, non-redundant collection of annotated, high-quality matrix-based transcription factor binding profiles, JASPAR FAM --a collection of familial TFBS models and JASPAR phyloFACTS-- a set of matrices computationally derived from statistically overrepresented, evolutionarily conserved regulatory region motifs from mammalian genomes. JASPAR phyloFACTS serves as a non-redundant extension to JASPAR CORE, enhancing the overall breadth of JASPAR for promoter sequence analysis. The new release of JASPAR is available [here].

(PS: Although NAR is an OA journal, the January 2006 issue isn't yet online. So for the time being, only the abstract is free online.)