Open Access News

News from the open access movement


Monday, November 29, 2004

Error correction and OA for bioinformatics data

Lee E. Eiden, A Two-Way Bioinformatic Street, Science Magazine, November 26, 2004 (accessible only to subscribers). An editorial. Excerpt: 'The rapid emergence of Web-based bioinformatics systems reflects the research community's attempts to embrace the biological complexity uncovered by high-throughput genome, transcriptome, and proteome data acquisition and the sheer size of the modern scientific endeavor. If information systems can match this complexity, biology will be enriched as a result. If not, scientific excitement may paradoxically be dampened by data flow....A primary ingredient for massive exchange of information among multiple bioinformatics tools and databases is curator tagging of input information to enable proofreading and data correction....Coupling a robust curator/user interface with the obligate entry of signaling data into a centralized repository upon publication, analogous to obligate submission of new DNA sequence information, is one way to combine greater intensity of curator/user interaction with increased database population, fostering greater data reliability. This might help both to accelerate the growth of cell signaling bioinformatics and to increase genuine open access to the knowledge derived from taxpayer-supported research.'