Open Access News

News from the open access movement


Wednesday, December 17, 2008

Paul Allen on the Allen Brain Atlas

Paul Allen, Piece of mind, The Economist, November 19, 2008. An op-ed. (Thanks to Gloria Tavera.)

The mystery of how the brain works is the most compelling question in science. ...

So six years ago I brought together a group of leading neuroscientists to find the basis for an approach that could advance the entire field of brain research. It was clear there needed to be a comprehensive database of information on where genes are turned on (or expressed) in the mouse brain—a map, or atlas, of the brain’s frontiers that would provide more encyclopedic information than any individual lab could afford to generate.

It seemed achievable. With the help of several noted researchers, I founded the Allen Institute for Brain Science in 2003 to undertake this project. Three years later, the institute had completed an atlas of gene expression in the mouse brain. ...

They released it to the public. Over the internet. Free. ...

Today we have many scientists using the atlas for their research into Alzheimer’s, bipolar disorders, Down’s syndrome, Parkinson’s, fragile x mental retardation and epilepsy. The atlas is also giving scientists insight into alcoholism, obesity, sleep, hearing and memory.

The greatest testament to what we did was that researchers of spinal-cord diseases, trauma and disorders approached the institute and asked us to create a spinal-cord atlas, which is now close to completion. We will launch the first phase of a human-brain atlas, a four-year project, in 2010. ...

Clearly the model of providing a freely accessible database is a successful one. In a sense, we have challenged other researchers to offer greater access to their findings. Will they take the challenge? My bet is that over the next 18 months we are going to see more open access and more collaboration. ...

See also our past posts on the Allen Brain Atlas.