Open Access News

News from the open access movement

Monday, November 17, 2008

Case study in open notebook science

Jean-Claude Bradley, From ONS to Peer Review: our JoVE Article is Published, Useful Chemistry, November 13, 2008.

Our article "Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling" is now published on the Journal of Visualized Experiments (JoVE). I am very pleased with this because it showcases some interesting approaches to communicate science that were not possible not so long ago.

First, and foremost, this demonstrates that lab notebook pages and blog posts can be used to support claims made in a peer reviewed article. ... When providing a reference for a melting point or spectrum, nothing is more relevant that the lab notebook page where the specific batch of product was obtained and characterized.

Second, we have demonstrated that it is possible carry out research under Open Notebook Science conditions, write an article openly on a wiki, post it on a pre-print server (like Nature Precedings) and finally publish it in an peer reviewed journal. ...

Third, this is a good example of the use of video to enhance the communication of a protocol for a chemical reaction. ...

Finally, JoVE is an example of an Open Access journal with some Web2.0 capabilities, like the ability to leave comments and label them as agreeing or disagreeing with the authors. The final article can now also serve as a location for continuing the scientific conversation.