Open Access News

News from the open access movement

Monday, October 01, 2007

NIH launches large OA SHARe database

NIH Launches Extensive Open-Access Dataset of Genetic and Clinical Data, a press release from the NIH, October 1, 2007.  Excerpt:

The National Institutes of Health (NIH) — the nation's medical research agency — is launching one of the most extensive collections of genetic and clinical data ever made freely available to researchers worldwide. Called SHARe (SNP Health Association Resource), the Web-based dataset enables qualified researchers to access a wealth of data from large population-based studies, starting with the landmark Framingham Heart Study. Funded by the NIH's National Heart, Lung, and Blood Institute (NHLBI), SHARe will accelerate discoveries linking genes and health, thereby advancing scientists' understanding of the causes and prevention of cardiovascular disease and other disorders....

SHARe is accessed through dbGaP, or the database of Genotypes and Phenotypes, a Web-based resource for archiving and distributing data from genome-wide association studies (GWAS). GWAS explore the associations between genes (genotype information) and observable traits (phenotypes), such as weight, cholesterol levels, or the presence or absence of a disease. Launched in December 2006, dbGaP was developed and is operated by the National Center for Biotechnology Information (NCBI), a division of NIH's National Library of Medicine (NLM).

The dbGaP also provides, for the first time, a central repository where study documentation, such as protocols and questionnaires, is linked to summary data of measured variables. For example, in Framingham SHARe, researchers can search for summary data on the average blood pressure value at a visit and easily find the associated protocol for measuring blood pressure....