Open Access News

News from the open access movement


Thursday, May 18, 2006

Launch of PLoS Clinical Trials

PLoS Clinical Trials has officially launched. From the site:

PLoS Clinical Trials (eISSN 1555-5887) is an international, peer-reviewed, open-access journal published online by the Public Library of Science (PLoS). The journal welcomes articles from around the globe reporting results of randomized trials in all fields of healthcare....PLoS Clinical Trials is run as a partnership between its in-house PLoS staff, and international Advisory and Editorial Boards, ensuring fast, fair and professional peer-review.

PLoS Clinical Trials aims to broaden the scope of clinical trials reporting by publishing the results of randomized trials in humans from all fields of healthcare. The journal's scope includes trials designed to assess the effects of different ways of treating, diagnosing, screening for, and preventing disease. Trials within the journal's scope may address any type of intervention relevant to healthcare. This may include, for example, reports of late phase II or phase III studies of pharmaceutical products, or medical devices, but also trials examining surgical therapies, mechanisms of health service delivery, and behavioral, lifestyle, psychological and educational interventions. We publish articles reporting the main results of a trial as well as interim, planned follow-up, and secondary analyses. In order to maximize the number of trials whose results are available in the public domain, publication decisions will not be affected by the direction of results, size or perceived importance of the trial. Confirmatory studies are welcome.

Each published paper in PLoS Clinical Trials will be linked to its corresponding entry in the relevant registry. PLoS is collaborating with Global Trial Bank (GTB), a non-profit subsidiary of the American Medical Informatics Association, to ensure that trial results are captured and stored in a computer-readable, standardized format. Once GTB is operational, results data from trials published in PLoS Clinical Trials will be coded and entered into the GTB database for open-access searching, browsing, and data-mining. Reciprocal links will be created between papers in PLoS Clinical Trials and the corresponding entries in GTB. More details on this collaboration will be available soon, both here, and on the GTB Web site....

All works published in PLoS Clinical Trials are open access. Everything is immediately available without cost to anyone, anywhere-to read, download, redistribute, include in databases, and otherwise use-subject only to the condition that the original authorship is properly attributed. Copyright is retained by the authors. Click here for more information on our license. Publishing costs are offset by a publication fee charged to authors. PLoS waives the fee for authors with insufficient funds. The ability to pay is not known to editors or reviewers, and never affects the decision whether to publish an article.

Also see the press release.