The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), has announced the latest round of mega genome sequencing projects - effectively the follow-ons to the Human Genome Project. These are designed to provide a sense of genomic context, and to allow all the interesting hidden structures within the human genome to be teased out bioinformatically by comparing them with other genomes that diverged from our ancestors at various distant times. Three more primates are getting the NHGRI treatment: the rhesus macacque, the marmoset and the orangutan. But alongside these fairly obvious choices, eight more mammals will be sequenced too....If you are not quite sure whom to vote for, you might want to peruse a great page listing all the genomes currently being sequenced for the NHGRI, which provides links to a document...explaining why each is important (there are pix, too). More seriously, it is worth noting that this growing list makes ever more plain the power of open genomics. Since all of the genomes will be available in public databases as soon as they are completed (and often before), this means that bioinformaticians can start crunching away with them, comparing species with species in various ways. Already, people have done the obvious things like comparing humans with chimpanzees, or mice with rats, but the possibilities are rapidly becoming extremely intriguing....And beyond the simple pairing of genomes, which yields a standard square-law richness, there are even more inventive combinations involving the comparison of multiple genomes that may reveal particular aspects of the Great Digital Tree of Life, since everything may be compared with everything, without restriction. Now imagine trying to do this if genomes had been patented, and groups of them belonged to different companies, all squabbling over their "IP". The case for open genomics is proved, I think.
Posted by
Peter Suber at 3/17/2006 03:48:00 PM.
The open access movement:
Putting peer-reviewed scientific and scholarly literature
on the internet. Making it available free of charge and
free of most copyright and licensing restrictions.
Removing the barriers to serious research.
I recommend the OA tracking project (OATP) as the best way to stay on top of new OA developments. You can read the OATP feed on a blog-like web page or subscribe to it by RSS, email, or Twitter. You can also help build the feed by tagging new developments you encounter.
