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David A. Vise, The Google Story: An Excerpt, Washington Post, November 14. Chapter 26, "Googling your genes", from Vise's new book, The Google Story (Delacorte Press, November 15, 2005). Excerpt:
Sergey Brin and Larry Page have ambitious long-term plans for Google's expansion into the fields of biology and genetics through the fusion of science, medicine, and technology. Their goal -- through Google, its charitable foundation, and an evolving entity called Google.org -- is to empower millions of individuals and scientists with information that will lead to healthier and smarter living through the prevention and cure of a wide range of diseases. Some of this work, done in partnership with others, is already under way, making use of Google's array of small teams of gifted employees and its unwavering emphasis on innovation, unmatched search capacity, and vast computational resources....One of the most exciting Google projects involves biological and genetic research that could foster important medical and scientific breakthroughs. Through this effort, Google may help accelerate the era of personalized medicine, in which understanding an individual's precise genetic makeup can contribute to the ability of physicians and counselors to tailor health care treatment, rather than dispensing medications or recommending treatments based on statistics or averages. New insights, new medicines, and the use or avoidance of certain foods and pharmaceuticals for people with specific genetic traits are among the possible outcomes. "Just think of the application of Google to genomics," said Hennessy. "There are large databases, lots of information, and the need for search." With the addition of specialized data, he said, Google's index could aid in new discoveries in genetics. "You want to be able to use a search system that is content-dependent, with the genome and structure of DNA already built in. It is one of many potential areas where you can see this so-called 'intelligent search' making a big difference. We are going to see more and more of it." Dr. Alan E. Guttmacher, deputy director of the National Human Genome Research Institute, said Google's involvement in genetics is particularly meaningful because of its capacity to search and find specific genes and genetic abnormalities that cause diseases. He also said that its massive computing power can be used to analyze vast quantities of data with billions of parts-quantities that scientists in laboratories do not have the capacity to process. The old model of a scientist working in a lab, he said, is being replaced by the new paradigm of a researcher working at a computer, connected to databases through the Internet, and doing simulations in cyberspace. "Until recently, the challenge has been gathering data," Guttmacher said. "Now, the bigger challenge is organizing and assessing it. Google-like approaches are the key to doing that. It completely accelerates and changes the way science is done. We are beginning to have incredible tools to understand the biology of human diseases in ways we never have before, and to come up with novel ways to prevent and treat them." |
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